The brain needs blood the carrier of oxygen and nutrients to function. If ever the supply is cut the brain cells start to die and the person may suffer a stroke. This happens either when the arteries are blocked by blood clots which in turn block the blood traveling to the brain and these blood vessels burst within the brain.
When this happens, the patient feels numbness in the limbs, paralysis in the face, finds it difficult to walk, talk and understand. A theory that is being researched and is still in the trial stage is that the blood vessels do not die but become dormant and stop working.
When this happens, the patient feels numbness in the limbs, paralysis in the face, finds it difficult to walk, talk and understand. A theory that is being researched and is still in the trial stage is that the blood vessels do not die but become dormant and stop working.
Stem cells taken from the bone marrow are transferred into brain of the person who has suffered a stroke may help wake the cells. These transferred cells act like a defibrillator on the dormant cells to wake them up and to start working and it also helps trigger an immune response for the brain to repair itself.
Cells which are taken from organs like donated heart tissue is said to have regenerative factors which regenerate the heart and other muscle functions in DMD patients.
This method is in phase 2 trial and it suggests that the stem cell therapy improves the heart function and movement of the upper limb in six months of being treated. The new trial hopes to gather information if repeated use of the stem cell method will improve movements in the upper body in DMD patients.
Stem cell therapy is also being used to treat boys and young men who suffer from a muscle wasting disease called Duchene muscular dystrophy (DMD).
The Muscular dystrophy is inherited. The heterogeneous neuromuscular disorders include Duchene and Becker muscular dystrophies (DMD and BMD, respectively). Those suffering from DMD show progressive muscle weakness and atrophy. This leads to exhaustion of muscular regeneration, fibrosis and disruption of muscle tissue.
Mutation of the gene is important for the dystrophin protein – actin and dystroglycan bindings - which results in DMD phenotype. While mutation is associated with BMD because of different mutations.
DMD affects over 3500 born males and is more common of the two. The patients slowly loose muscle control and become wheel chair bound before the age of 12 and die of respiratory insufficiency.
Cells which are taken from organs like donated heart tissue is said to have regenerative factors which regenerate the heart and other muscle functions in DMD patients.
This method is in phase 2 trial and it suggests that the stem cell therapy improves the heart function and movement of the upper limb in six months of being treated. The new trial hopes to gather information if repeated use of the stem cell method will improve movements in the upper body in DMD patients.
Stem cell therapy is also being used to treat boys and young men who suffer from a muscle wasting disease called Duchene muscular dystrophy (DMD).
The Muscular dystrophy is inherited. The heterogeneous neuromuscular disorders include Duchene and Becker muscular dystrophies (DMD and BMD, respectively). Those suffering from DMD show progressive muscle weakness and atrophy. This leads to exhaustion of muscular regeneration, fibrosis and disruption of muscle tissue.
Mutation of the gene is important for the dystrophin protein – actin and dystroglycan bindings - which results in DMD phenotype. While mutation is associated with BMD because of different mutations.
DMD affects over 3500 born males and is more common of the two. The patients slowly loose muscle control and become wheel chair bound before the age of 12 and die of respiratory insufficiency.
Mutation of the dystrophin gene can lead to partially working protein leading to mild BMD. There are no therapies available. Cell based therapies are made in an effort to promote muscle regeneration in the hope that the cells will occupy the muscle again and the functions of the muscle will improve.
Injection of adult myoblasts leads to development of new muscle fibers, but there are limitations there is poor cell survival and migration is limited. Stem cells are considered an alternative to myoblasts.
Stem cells have shown encouraging results in treating leukemia, Parkinson's disease, stroke, and muscular dystrophies.
Embryonic stem cells derived from mammalian embryos have the potential to treat all human diseases. There are many ongoing studies which focus on this possibility. Stem cells have been identified in tissues where they maintain, generate and replace ill cells or when the need arises during a tissue injury. They regenerate specific tissue type.
Injection of adult myoblasts leads to development of new muscle fibers, but there are limitations there is poor cell survival and migration is limited. Stem cells are considered an alternative to myoblasts.
Stem cells have shown encouraging results in treating leukemia, Parkinson's disease, stroke, and muscular dystrophies.
Embryonic stem cells derived from mammalian embryos have the potential to treat all human diseases. There are many ongoing studies which focus on this possibility. Stem cells have been identified in tissues where they maintain, generate and replace ill cells or when the need arises during a tissue injury. They regenerate specific tissue type.
To know more
on new stem cell findings, log on to www.cordlifeindia.com.
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